GENETIC ANALYSIS OF OSTEOPOROSIS IN GREECE

Fracture Data
Fracture Data Available ?: 
Yes
Subjects in study with DNA available and fracture information?: 
402
Number of MEN with ALL-TYPE of fracture?: 
35
Can you discriminate between PREVALENT and INCIDENT fractures?: 
Yes
Number of WOMEN with ALL-TYPE of fracture?: 
298
Number of MEN with VERTEBRAL fracture?: 
5
Number of WOMEN with VERTEBRAL fracture?: 
29
Number of MEN with HIP fracture?: 
18
Number of WOMEN with HIP fracture?: 
166
Number of MEN with WRIST fracture?: 
4
Number of WOMEN with WRIST fracture?: 
95
Prevalent Fractures
Minimum age of inclusion of the PREVALENT fracture events?: 
30
PREVALENT fractures (already occurred at time of study enrollment): 
ALWAYS ascertained by X-ray films or radiology reports
hands/fingers, feet/toes, face/skull fractures were included
high trauma fractures (automobile accident, fall from a height, etc) were excluded
Incident Fractures
Do you have in your study INCIDENT fractures?: 
Yes
INCIDENT fractures (occurring after study enrollment): 
ALWAYS ascertained by X-ray films or radiology reports
hands/fingers, feet/toes, face/skull fractures were included
high trauma fractures (automobile accident, fall from a height, etc) were excluded
Minimum age of inclusion of the INCIDENT fracture events?: 
35
Vertebral Fractures
Do you have in your study VERTEBRAL fractures?: 
Yes
Can you discriminate between PREVALENT and INCIDENT VERTEBRAL fractures: 
Yes
Were VERTEBRAL fractures ALWAYS ascertained by X-ray films or radiology reports?: 
Yes
Was MORPHOMETRY (vertebral body heights) from lateral X-rays assessed?: 
Yes
If YES, was McCloskey-Kanis definition used?: 
Yes
If YES, was Genant's semi-quantitative definition used: 
Yes
If YES, could you retrieve the three vertebral body height measurements?: 
No
If YES, what was the relative reduction cutoff used?: 
20%
If YES, what was the cutoff for absolute height reduction of vertebral body?: 
4 mm
If YES, what was the reference for comparison of posterior height?: 
Adjacent vertebrae