Rotterdam Study I

A prospective cohort study that started in 1990 in Ommoord, a suburb of Rotterdam, The Netherlands among 10,994, men and women aged 55 and over. The main objective of the Rotterdam Study is to investigate the prevalence and incidence of and risk factors for chronic diseases in the elderly. The chronic diseases of interest are cardiovascular, neurological, locomotor and ophthalmologic diseases. The findings from the Rotterdam Study will hopefully contribute to a better prevention and treatment of chronic diseases in the elderly. The osteoporosis genetic studies comprise 5746 individuals with information on Fx/DXA and GWAs assesment.

General Design
Study design: 
Cohort study
Population-based
Recruitment target: 
Individuals
Target number of participants: 
7 983
Target number of participants with samples: 
7 983
Data Collection
Data sources: 
Questionnaires
Physical measures
Biological samples
Electronic health databases (death or hospitalization registries, etc.)
Pharmacy records
Sample Collection
Biological samples: 
Blood
Marker Paper
Marker paper: 
The Rotterdam Study: 2014 objectives and design update.
Pubmed Id: 
PUBMED 24258680
Authorization
Fernando Rivadeneira authorised the contribution to GEFOS on Jan 2007

Participants Selection
Selection criteria: 
Age:
    Minimum 55
Country:
    Netherlands
Territory:
    Ommoord distric, Rotterdam
Ethnic origin:
    European
Health status:
    Alive
Access
Access to external researchers or third parties provided or foreseen for
Data (questionnaire-derived, measured…): 
Yes
Biological samples: 
Yes
Status
Preparation phase / Pilot: 
From 1990
Baseline recruitment / initial data collection: 
From 1990 to 1992
Follow-up of participants: 
From 1990
Current number of participants recruited: 
7 983
Current number of participants with samples: 
6 318

Acronym: 
RS-I
Website: 
http://www.epib.nl/research/ergo.htm